Pernicious anaemia: recognition, diagnosis and management

Introduction  Pernicious anaemia is an autoimmune condition that affects the stomach; however, it is the resultant vitamin B12 deficiency that causes the symptoms commonly associated with pernicious anaemia. It is characterised by inflammation and atrophy of the gastric mucosa resulting in reduced production of intrinsic factor and gastric acid. In many cases, auto-antibodies cause further … Continue reading Pernicious anaemia: recognition, diagnosis and management