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In this issue

Insight

Illustration of a heart inside a pill bottle

Cholesterol-lowering statin therapy for healthy people is not as simple as 'yes' or 'no'Subscription

By

Recent reports of large trials extolling the virtues of statins have led many to believe that low-risk patients should take them, but an examination of the evidence provides food for thought.

CPD article

Micrograph of multiple myeloma tumour cells (green) and bone cells (red) growing on a scaffold made of silk protein (purple), designed to resemble bone material

Multiple myeloma: pharmacological management

By

Although multiple myeloma is currently regarded as being incurable in the majority of patients, the outlook for patients diagnosed with the condition has improved markedly over the last 40 years, with survival rates quadrupling. Significant advances in both treatment and supportive therapies have contributed to these improved outcomes and are discussed in this article.

Perspective article

Teenager gets an HPV vaccine injection

The impact of the human papillomavirus vaccine in Scotland: a changing landscapeSubscription

By ,

In the UK, cervical cancer is the second most common cancer in women aged under 35 years. Human papillomavirus (HPV) types 16 and 18 (both high risk) are necessary precipitants in at least 70% of cervical cancers but may contribute to more than 80% of cervical cancers in Scotland. Both the prophylactic bivalent (Cervarix; GlaxoSmithKline) and quadrivalent (Gardasil; Merck) vaccines prevent infection with HPV types 16 and 18, and have been shown to induce avid and sustained neutralising ...

Review

Fluoroscopic examination of gastrointestinal (GI) tract showing inflammatory bowel disease (IBD)

Management of patients with inflammatory bowel disease: current and future treatmentsSubscription

By ,

Inflammatory bowel disease (IBD) is characterised by chronic inflammation of the gastrointestinal tract and affects patients’ quality of life. Treatment of IBD involves induction and maintenance of remission. Current available therapies include anti-inflammatory aminosalicylates and corticosteroids, immunosuppressive agents, antibiotics and biologic agents. Some patients are not fully responsive to conventional treatment or lose efficacy over time. Recently approved ...

Short communications

Why there is evidence to be hopeful about neuroscience and drug developmentSubscription

By

We continue to see media reports describing how pharmaceutical companies are cutting or altogether halting investment in neuroscience, thereby eliminating the possibility of innovative treatments for devastating brain disorders such as depression and

Medicines optimisation service in Weymouth and PortlandSubscription

By

In September 2015, the medicines optimisation service (MOS) was set up within Weymouth and Portland, Dorset. The MOS pharmacist conducts in-depth domiciliary consultations with patients to improve adherence and prevent harm from inappropriate medicines administration or prescribing. The service targets patients aged over 75 years with polypharmacy, on admissions avoidance care plans or living in care homes.

Research briefing

Ovarian cancer cells

Researchers discover molecule that inhibits cancer cell stress responseSubscription

7 MAR 2017

Scientists find a new chemical probe that is a potent inhibitor of human cancer cell proliferation in vitro, with potential applications against many cancers.

Molecular structure of ketamine

Antidepressant response associated with increased resilience to stress in miceSubscription

6 MAR 2017

Researchers say their study using a mouse model of chronic social defeat stress could be applied to identify novel drug targets for depression therapies.

Micrograph of Staphylococcus aureus bacteria (yellow) on human nasal epithelial cells

Salicylic acid exposure might increase risk of Staphylococcus aureusSubscription

6 MAR 2017

Animal research suggests that frequent consumption of aspirin could contribute to S. aureus infection.

Micrograph of the Zika virus

Zika candidate vaccine confers durable protection in animal trialsSubscription

3 MAR 2017

Researchers found that a single dose of their mRNA-based Zika vaccine could protect mice for up to five months.

Clinical Pharmacist

CP March 2017, Vol 9, No 3

Cover Story:

The impact of the human papillomavirus vaccine in Scotland: a changing landscape

Read more…

Clinical Pharmacist

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Clinical Pharmacist is a monthly, peer-reviewed journal that provides authoritative resources on the clinical management of disease in relation to medicines and up-to-date information about advances in pharmacy and drug development. Clinical Pharmacist publishes Review articles, Perspectives, evidence-based CPD articles and Research articles on topics from drug discovery to clinical pharmacology and pharmacy.

The international audience of Pharmaceutical Journal Publications consists of pharmacists, pharmaceutical scientists and healthcare professionals. The journal is available to 44,000 members of the Royal Pharmaceutical Society, as well as non-member individual subscribers and subscribing institutions.