CP, March 2017, Vol 9, No 3

Multiple myeloma: pharmacological management

Although multiple myeloma is currently regarded as being incurable in the majority of patients, the outlook for patients diagnosed with the condition has improved markedly over the past 40 years, with survival rates quadrupling. Significant advances in both treatment and supporti…

The impact of the human papillomavirus vaccine in Scotland: a changing landscape

In the UK, cervical cancer is the second most common cancer in women aged under 35 years. Human papillomavirus (HPV) types 16 and 18 (both high risk) are necessary precipitants in at least 70% of cervical cancers but may contribute to more than 80% of cervical cancers in Scotland. Both the prophylac…

Cholesterol-lowering statin therapy for healthy people is not as simple as ‘yes’ or ‘no’

Recent reports of large trials extolling the virtues of statins have led many to believe that low-risk patients should take them, but an examination of the evidence provides food for thought.…

Researchers discover molecule that inhibits cancer cell stress response

Scientists find a new chemical probe that is a potent inhibitor of human cancer cell proliferation in vitro, with potential applications against many cancers.…

Management of patients with inflammatory bowel disease: current and future treatments

Inflammatory bowel disease (IBD) is characterised by chronic inflammation of the gastrointestinal tract and affects patients’ quality of life. Treatment of IBD involves induction and maintenance of remission. Current available therapies include anti-inflammatory aminosalicylates and corticoste…

Antidepressant response associated with increased resilience to stress in mice

Researchers say their study using a mouse model of chronic social defeat stress could be applied to identify novel drug targets for depression therapies.…

Salicylic acid exposure might increase risk of Staphylococcus aureus

Animal research suggests that frequent consumption of aspirin could contribute to S. aureus infection.…

Zika candidate vaccine confers durable protection in animal trials

Researchers found that a single dose of their mRNA-based Zika vaccine could protect mice for up to five months.…

E-cigarettes linked to increased cardiovascular risk factors

University of California researchers found that e-cigarette users were more likely to show increased cardiac sympathetic activity and higher levels of oxidative stress.…

Diazepam should not be added to NSAIDs for acute lower back pain, researchers say

Study results show that 22% of patients taking placebo with naproxen for back pain reported moderate to severe pain, compared with 32% of patients taking diazepam with naproxen.…