News People with sickle cell disease face racism and ‘sub-standard care’, finds report A report commissioned by the NHS Race and Health Observatory recommends that more sickle cell training for healthcare professionals, including primary care, is needed.…Published: 19 June 2025
News MHRA publishes ‘world first’ decentralised manufacturing guidance The guidance will inform the manufacture of medicines with a short shelf-life or highly personalised medicines at sites within or in close proximity to hospitals.…Published: 13 June 2025
News NHS pharmacogenomics trial expands to 20 sites across England The PROGRESS trial is planned to finish in early 2026, with an impact assessment produced in the fourth quarter of 2025/2026.…Published: 29 May 2025
News NICE recommends capivasertib for advanced breast cancer Clinical trial results revealed that capivasertib, taken with fulvestrant, can provide advanced breast cancer patients with an additional four months before their cancer progresses.…Published: 11 April 2025
News Genetic testing could prevent three-quarters of avoidable side effects of some medicines, study suggests Researchers found that patients experiencing adverse drug reactions to treatments for psychiatric disorders and cardiovascular problems could benefit the most from personalised prescribing with pharmacogenomics.…Published: 1 April 2025
News Rapid on-site genetic sequencing could help curb antimicrobial-resistant outbreaks, says MHRA Researchers found that rapid on-site genetic sequencing detects bacterial infections within two days, which is “significantly faster“ than traditional methods.…Published: 7 March 2025
News Nine in ten people would accept a pharmacogenomics test, reveals survey The majority of respondents to a survey said they would be motivated to take a pharmacogenomics test to enhance drug effectiveness and reduce the risk of adverse drug reactions.…Published: 21 February 2025
News Pharmacogenomics trial expands across England Programme co-ordinators are aiming to recruit a further 1,450 people to the second phase of the PROGRESS trial, which is the first in the UK to introduce genetic testing before prescribing in primary care.…Published: 11 February 2025
News NICE approves gene-editing sickle cell therapy for NHS in England Exagamglogene autotemcel, also known as exa-cel, is now recommended for NHS use, reversing previous draft guidance.…Published: 4 February 2025
Opinion Top ten features of 2024 From dangerous new synthetic opioids to the use of artificial intelligence to transform drug discovery, our most popular features this year have covered a wide array of topics.…Published: 27 December 2024