Investigational medicines

Experimental menopause drug cuts number of hot flushes

An experimental drug has been shown to dramatically cut the number of hot flushes in women with severe menopause symptoms.…

How Rachel Macdonald got involved in research in a community pharmacy

Rachel Macdonald, professional services pharmacist for PCT Healthcare Ltd, recently participated in the Salford Lung Study in community pharmacy.…

Large proportion of stalled drug trial data is not being published, study finds

A vast amount of drug development data are being lost through the failure to publish the results of a high proportion of trials, particularly of drugs that did not go on to be approved, a study suggests. …

Breakthrough in targeting KRAS gene mutation implicated in many cancers

Researchers have identified an agent that interferes with the cell signalling protein KRAS and which produces a dose-dependent reduction in tumour growth in a mouse model.…

Ebola research gets a 280m euro boost from EU and drug industry

The European Union has pledged 280m euro to a research project to develop vaccines and diagnostic tests for Ebola.…

Phase II clinical trials for Ebola vaccine planned for early 2015

Experts involved in the organisation of clinical research on Ebola vaccines intend to move to randomised controlled phase II trials in early 2015.…

European Medicines Agency to review Ebola therapies

Experimental Ebola treatments are to be reviewed by the European Medicines Agency as part of the international response to the disease outbreak in West Africa.…

Experimental antifungal drug causes fewer side effects than voriconazole

A new experimental anti-fungal treatment is no less effective than its predecessor, but exposes patients to fewer side effects, a study has found.…

Potential role for benralizumab in COPD patients with eosinophilia

Benralizumab therapy led to a numerical, albeit not statistically significant, improvement in COPD exacerbations and lung function compared with placebo.…

BioCryst remains hopeful of FDA approval for its single-dose influenza drug despite mixed results

An experimental single-dose influenza drug has demonstrated mixed results in treating adult patients with flu when administered within 48 hours of the onset of symptoms.…