Meta-analysis

Triptans should be considered as preferred first-line treatment for acute migraine, research concludes

From head-to-head comparisons between active interventions, the meta-analysis showed that eletriptan was the most effective drug for pain freedom at two hours post dose.…

Tirzepatide more effective in blood sugar control and weight loss than semaglutide, meta-analysis finds

Analysis of 22 studies revealed that tirzepatide was more effective in reducing body weight than semaglutide at all respective doses.…

Honey effective at relieving URTI symptoms, analysis concludes

Honey is superior to usual care for improving symptoms of upper respiratory tract infection symptoms, researchers have concluded.…

Ward-based pharmacists are beneficial and cost-effective

The National Institute for Health and Care Excellence (NICE) guideline NG94, published in March 2018, focused on organising and delivering emergency and acute medical care for people aged over 16 years in the community and in hospital[1] . The main aims of the guideline were to reduce the n…

Methylphenidate should be first choice ADHD drug in children, Lancet study concludes

The preferred first-line treatment for attention-deficit hyperactivity disorder in children is methylphenidate, a review of the evidence has concluded.…

Antidepressants linked with increased risk of VTE

Depression and use of antidepressants are each associated with an increased risk of venous thromboembolism, a study has revealed. Although the mechanism underlying these associations is not yet understood.…

Benefits of smoking cessation medicines decline over first year

Research has shown that the proportion of people who benefit from smoking cessation medicines dwindles over the first year of use…

Antidepressants more effective than placebo for adults with acute major depressive disorder

Antidepressants are more effective than placebo for the acute treatment of adults with unipolar major depressive disorder, according to a new meta-analysis.…

Evidence for prenatal vitamin D supplementation too weak to make recommendations

A review of data from 43 trials suggests that prenatal vitamin D has positive neonatal outcomes, but the current evidence base does not cover all aspects of outcomes and safety…

Antidepressants linked to increased risk of mortality and new cardiovascular events

Antidepressant use increases the risk of mortality and new cardiovascular events, according to a study published in Psychotherapy and Psychosomatics…