Phase II research

MDMA could enhance psychotherapy outcomes in people with PTSD

Research has shown ‘marked improvements’ in PTSD symptoms after MDMA use during psychotherapy.…

RNA interference therapies could be on the cusp of success

This new way of modifying problematic gene expression has had a rocky start — but things are looking up.…

Immunotherapy for type 1 diabetes: what’s in the pipeline?

For many autoimmune diseases, such as rheumatoid arthritis and psoriasis, drugs that work by targeting components of the immune system are providing relief for millions of patients. However, there is no immunotherapy currently licensed for type 1 diabetes, and the reasons for this are multifold. A n…

Topical gel could improve treatment of erectile dysfunction

Researchers find glyceride trinitrate gel to be an effective treatment for mild erectile dysfunction…

Zika vaccine development: two years on from the outbreak

Two years after the World Health Organization declared the Zika virus outbreak a Public Health Emergency of International Concern, researchers have made good progress in developing vaccines against the disease, with some candidates now in phase II trials. However, the brief nature of the outbreak is…

Innovation in acne treatment is long overdue but the treatment pipeline looks promising

Current treatments for acne are effective but regimens are complex and side effects are common. Better understanding of the pathology of acne is leading to identification of new, safer, treatment targets, and dermatologists and researchers in the field are excited about the pipeline.…

‘Living drug’ may soon be approved by the FDA for treatment of acute lymphoblastic leukaemia

CAR-T cell immunotherapy recommended for approval and may get FDA go ahead by the end of 2017.…

Analysis estimates more than 30 Alzheimer’s drugs will have launched by 2022

Over the next 5 years, 27 phase III and 8 phase II Alzheimer’s drugs may be launched, according to a pipeline analysis carried out by ResearchersAgainstAlzheimer’s…

Experimental menopause drug cuts number of hot flushes

An experimental drug has been shown to dramatically cut the number of hot flushes in women with severe menopause symptoms.…

Searching for new medicines to treat alcohol addiction

Only a few drugs are licensed to treat alcoholism and, although reasonably effective, they are not suitable for everyone. Increased understanding of the underlying neuroscience of alcohol addiction is revealing a wealth of new possible drug targets, and a number of trials are under way.…