Chip diagnoses type 1 diabetes in minutes

Researchers have used nanotechnology to develop a plasmonic gold chip that can diagnose type 1 diabetes within minutes.

Type 1 diabetes can be clinically indistinguishable from type 2 diabetes and a definitive diagnosis, using radioimmunoassay, is slow and expensive to perform. Researchers, led by Brian Feldman, from Stanford University, have used nanotechnology to develop a plasmonic gold chip that can diagnose the disease within minutes.

The chip uses near-infrared fluorescence to detect islet cell-targeting autoantibodies in a fingerprick blood sample, and costs just $20 to produce, according to the report in Nature Medicine (online, 

When tested in diabetes patients and healthy controls, the chip had high sensitivity and specificity for the diagnosis of type 1 diabetes. It can also be used to discover previously unknown biomarkers of type 1 diabetes, adds Feldman.

Last updated
Citation
The Pharmaceutical Journal, PJ, 26 July/2 August 2014, Vol 293, No 7820/1;293(7820/1):DOI:10.1211/PJ.2014.20065898