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Glenis K Scadding

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Glenis K Scadding is honorary consultant physician in allergy and rhinology, Department of Allergy and Medical Rhinology, Royal National Throat Nose and Ear Hospital, 330 Gray’s Inn Road, London.

Allergic rhinitis: impact, diagnosis, treatment and management

Allergic rhinitis results from an immunological abnormality in which atopic individuals produce immunoglobulin E (IgE) to allergens (e.g. pollen, house dust mites, animal dander and moulds). IgE activates mast cells, which respond by releasing inflammatory mediators. Histamine stimulates the early s…