News | Neurological conditions

Feature

Everything you need to know about NICE’s decisions on ‘game-changing’ Alzheimer’s drugs

In August and October 2024, the National Institute for Health and Care Excellence issued a decision not to recommend two new drugs for Alzheimer’s disease that experts had previously welcomed for their disease-modifying effects. We explain the reasons behind their decisions.…

Published: 14 November 2024

News

NICE rejects second Alzheimer’s disease treatment for NHS use

Clinical trial evidence reveals that there are “significant health risks” linked to donanemab, with a third of patients experiencing amyloid-related imaging abnormalities as a result of brain swelling and bleeding.…

Published: 24 October 2024

News

Men taking valproate advised by MHRA to use effective contraception

The regulator advises that males and their partners should use effective contraception during, and for at least three months after, valproate treatment.…

Published: 9 September 2024

News

Alzheimer’s treatment lecanemab too costly for NHS, says NICE draft guidance

The National Institute for Health and Care Excellence has determined that the small benefit that lecanemab provides patients in the early stages of Alzheimer’s disease does not justify the cost to the NHS.…

Published: 23 August 2024

News

More than 2,000 patients tested in UK’s first routine genotyping project for clopidogrel prescribing

Exclusive: The genotyping project at NHS Tayside identified 2,300 patients, 29% of whom emerged as ‘poor’ or ‘intermediate’ CYP2C19-clopidogrel metabolisers.…

Published: 19 August 2024

Opinion

Lessons from testing 2,300 patients at the UK’s first CYP2C19 genotyping system

Specialist clinical pharmacist Alex Matos explains what his team has learned in the two years since setting up the NHS Tayside project to genotype acute stroke patients with an indication for clopidogrel.…

Published: 19 August 2024

Feature

Changes in migraine treatment: how new classes of drugs can provide additional options for patients and prescribers

This episode of The PJ Pod looks at recent changes to National Institute for Health and Care Excellence guidance on the treatment of acute and chronic migraine and what pharmacists should expect from the new class of gepant drugs.…

Published: 2 August 2024

News

NICE recommends tenecteplase for treating acute ischaemic stroke patients

Tenecteplase was found to be as effective as alteplase, which is more expensive, and the National Institute for Health and Care Excellence said its decision could save the NHS “millions”.…

Published: 26 July 2024

News