Medicines management in adult patients undergoing liver transplantation
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- Question 1 of 15
1. Question
Which of these factors does not influence drug pharmacokinetics in advanced liver disease?
CorrectIncorrect - Question 2 of 15
2. Question
What class of drugs should be avoided in patients with advanced liver disease?
CorrectIncorrect - Question 3 of 15
3. Question
What is the mechanism of action of tacrolimus?
CorrectIncorrect - Question 4 of 15
4. Question
Which statement is false? Therapeutic drug monitoring is required for immunosuppressants, such as tacrolimus, ciclosporin and sirolimus, to:
CorrectIncorrect - Question 5 of 15
5. Question
Why is IV administration of calcineurin inhibitors not preferred?
CorrectIncorrect - Question 6 of 15
6. Question
Which drug does not interact with the calcineurin inhibitor ciclosporin?
CorrectIncorrect - Question 7 of 15
7. Question
Patients who wish to travel after a liver transplant should be counselled on which of the following issues?
CorrectIncorrect - Question 8 of 15
8. Question
In addition to immunosuppression, supportive medication is commonly prescribed post liver transplantation. What are two correct indications for supportive medication?
CorrectIncorrect - Question 9 of 15
9. Question
Which of the following would NOT be an indication for liver transplantation?
CorrectIncorrect - Question 10 of 15
10. Question
A patient is on day seven post liver transplant, which has gone well. Renal and liver function is satisfactory. What would be a typical target trough level for tacrolimus?
CorrectIncorrect - Question 11 of 15
11. Question
What is the mechanism of action of antithymocyte globulin?
CorrectIncorrect - Question 12 of 15
12. Question
Five years after a liver transplant, a patient presents with weight loss and lymphadenopathy on a computerised tomography scan. Which infection is associated with post-transplant lymphoproliferative disease?
CorrectIncorrect - Question 13 of 15
13. Question
A patient presents with diarrhoea, ten months post liver transplant. Colonic biopsy shows viral inclusion bodies. Which infection is likely to be causing their diarrhoea?
CorrectIncorrect - Question 14 of 15
14. Question
A patient develops a severe fungal infection requiring treatment with voriconazole. Their immunosuppression regimen contains tacrolimus. What may be the appropriate course of action that the patient’s transplant centre would recommend?
CorrectIncorrect - Question 15 of 15
15. Question
Timely patient follow-up is essential post-transplant for:
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