Multiple sclerosis: disease-modifying therapies
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- Question 1 of 15
1. Question
What is the usual age of presentation of multiple sclerosis?
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2. Question
What is the most common type of presentation in multiple sclerosis?
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3. Question
How many disease modifying treatments are currently available for relapsing remitting multiple sclerosis (RRMS)?
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4. Question
What is the predominant aim of treatment with disease modifying treatments in relapsing remitting multiple sclerosis (RRMS)?
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5. Question
The main target for disease modifying treatments (DMTs) is T and B lymphocytes, though different mechanisms of action. Which of the following DMTs acts by altering the trafficking (movement) of lymphocytes by preventing their egress into the blood stream, retaining them in the lymph nodes?
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6. Question
Who is the most appropriate person to diagnose multiple sclerosis and determine eligibility for disease modifying treatments?
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7. Question
John Cunningham virus serology is measured to determine risk of progressive multifocal leukoencephalopathy for which disease modifying treatments?
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8. Question
Which disease-modifying treatment requires a genetic test for CYP2C9 to determine their metaboliser status?
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9. Question
Which screening tests are recommended prior to starting the first disease-modifying treatment?
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10. Question
Flu-like symptoms for 24 hours after the dose is common with which of the following disease-modifying treatments?
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11. Question
Which of the following disease-modifying treatments always requires cardiac monitoring with the first dose?
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12. Question
How long should a patient be on disease-modifying treatment for before an assessment on efficacy can be made?
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13. Question
Which of the following disease-modifying treatments can be used to treat primary progressive multiple sclerosis?
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14. Question
Timing of disease-modifying treatment (DMT) initiation in relation to vaccines is important as live vaccines are contraindicated while immunosuppressed and inactivated vaccines may be less effective. If a live vaccine is required, when should it be given in relation to the first immunosuppressive DMT?
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15. Question
Which of the following side effects are common with dimethyl fumarate and can be reduced by taking the tablets after meals high in fats or proteins?
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