Genetics

Newborn genome screening: a step too far?

A project to screen the genomes of 100,000 babies for rare diseases is set to begin recruiting in 2023, but it will face ethical and societal challenges.…

Pharmacists should be able to refer patients to NHS genomics services, says Royal Pharmaceutical Society

In the Society's consultation response, Thorrun Govind said there needs to be an explanation of how pharmacy staff can enrich and complement the NHS Clinical Genomics Service.…

Clinical impact of CFTR modulator therapy roll-out

An overview of the essential role a specialist cystic fibrosis pharmacist has in the optimisation of CFTR modulator combinations and a closer look at real-world clinical outcomes.…

How we set up the UK’s first clopidogrel genomics testing system

Specialist clinical pharmacist Alex Matos explains how he has been implementing pharmacogenomics in daily use on the acute stroke ward.…

Safety review launched into anti-epileptic medicine topiramate over fears of harm to unborn children

The review was prompted by study results that showed there was a two- to four-fold increased risk of developmental disorders or learning difficulties in children exposed to topiramate before birth.…

Pharmacogenomic testing may aid antidepressant prescribing, study results show

Researchers found that patients with major depressive disorder whose treatment was guided by genetic testing were more likely to receive an antidepressant with no drug–gene interaction.…

Everything you need to know about the NHS genomic medicine service

A closer look at the progress made so far on NHS England’s new national genomic medicine service.…

Wilson’s disease: diagnosis and management

An overview of the causes, signs, symptoms and management of Wilson’s disease, an autosomal recessive genetic disorder characterised by the accumulation of copper in various body tissues.…

Help us develop an e-learning module on cell and gene therapies

Cell and gene therapies are emerging types of medicines that aim to provide treatment opportunities to individuals, with application across a number of illnesses. Cell and gene therapies are types of advanced therapy medicinal products (ATMPs) that are biological medicines based on either genes,…

Pharmacogenetic testing in community pharmacy could improve drug selection and cut adverse reactions, study finds

Researchers have estimated that an actionable drug–gene interaction was present for around 20% of all new prescriptions for 56 common medicines.…