Bone drug could help prevent breast cancer in BRCA1 carriers Blocking RANK ligand with denosumab reduced proliferation of breast cells from women at high genetic risk of breast cancer.…
Resistance to antimalarial atovaquone does not spread Atovaquone could be used more widely to treat malaria since resistance does not spread to subsequent generations of the malaria parasite.…
Autism: in search of new drug targets Genetic discoveries have invigorated autism research and raised the possibility of finding drug targets based on autism’s underlying pathophysiology, rather than merely treating symptoms.…
FDA approves venetoclax for chronic lymphocytic leukaemia The US Food and Drug Administration has approved venetoclax for the treatment of chronic lymphocytic leukaemia.…
Migalastat set for approval as first oral therapy for Fabry disease The European Medicines Agency has recommended the approval of migalastat for the treatment of the rare genetic disorder Fabry disease.…
Gene therapy for ‘bubble boy’ syndrome on track for EU approval Children with an extremely rare immune deficiency disease are set to have access to gene therapy, following a recommendation for approval by the European Medicines Agency.…
Study identifies how immune cells attack malignant tumours New research shows how the genetic diversity of malignant tumours is identified by the body’s immune system, opening the door to the development of improved anticancer therapies.…
Ivacaftor shows good safety profile in young children Research shows that cystic fibrosis drug ivacaftor is well tolerated but needs close monitoring in patients aged 2–5 years.…
Computer programme predicts antibiotic resistance in three minutes Mykrobe software uses genome sequence data to predict resistance to 12 antibiotics in retrospective study.…
Gene editing used to treat muscular dystrophy in mice CRISPR/Cas9 system injected into muscle or bloodstream restored function of dystrophin gene, marking an important step in gene therapy research.…
