Injection of modified cells reduces inflammation in arthritis sufferers A single injection of a patient’s own modified dendritic cells appears to be safe and to have anti-inflammatory and immunoregulatory effects in rheumatoid arthritis.…
Modified herpes virus therapy shows promise in melanoma A virus-derived oncolytic immunotherapy has shown activity against melanoma in a phase III clinical trial, researchers report in the Journal of Clinical Oncology.…
Ciclosporin fails to demonstrate protection from neuronal damage during thrombolysis The phase II study looked at the potential neuroprotective effect of ciclosporin in 127 stroke patients who also received thrombolysis therapy.…
Combining chemotherapy with immunotherapy is promising treatment for advanced prostate cancer Using mouse models, researchers learn that immune cell manipulation in combination with chemotherapy achieves prostate cancer remission.…
Melanoma therapy that targets PD-1 recommended for EU approvalThe European Medicines Agency has recommended granting a marketing authorisation for new melanoma treatment nivolumab.…
New therapy to tackle treatment-resistant cancers Scientists have developed a therapy that could outsmart cancer cells that have become immune to certain treatments, according to a study published in Cancer Cell.…
Broadly neutralising antibody shows some success in treating patients with HIV A potent type of antibody therapy trialled in HIV patients for the first time has been shown to reduce the amount of virus in patients’ blood.…
Small molecule could pave way for novel vaccine adjuvants Identification and characterisation of a small molecule that targets protein receptors that stimulate the immune system could lead to novel vaccine adjuvants and anti-tumour agents.…
Researchers create personalised vaccines for patients with advanced melanoma A study has revealed that targeting patient-specific markers in advanced melanoma tumours effectively triggers an immune response.…
Nucleic acids made into furry nanoballs modulate immune system Short nucleic acids mounted on to nanoparticles could prove to be novel immunomodulators, according to research published in PNAS.…