Researchers identify new anti-inflammatory compounds Two separate research groups have identified compounds that can inhibit components of the immune system that are involved in several inflammatory disorders.…
Researchers show how MRI data can help predict drug efficacy Scientists have developed a method for using data from functional magnetic resonance imaging to shed light on how central nervous system drugs cause changes in brain activity.…
Tizanidine interactions Careful titration of the skeletal muscle relaxant tizanidine is required to avoid dose-related hypotension, and its serum levels can be increased by drugs that inhibit CYP1A2.…
Regulator set to develop guidance for pharmacist prescribersThe General Pharmaceutical Council is considering producing its own guidance for pharmacist prescribers as it expects the role to develop.…
Structure of translocator protein hints at role in disease Two research groups have independently solved the structures of similar translocator proteins, offering clues about its function that could spur the development of targeted drugs.…
UK government provides £13.7m for ‘stratified medicine’ collaborationsThe UK government has announced £13.7m of funding for four ‘stratified medicine’ collaborations with the Medical Research Council.…
Oestrogen receptor ligands show promise for treating endometriosis Researchers studying endometriosis have discovered a potential way to treat the disease that avoids many of the side effects seen with existing therapies.…
The Pharmaceutical Journal’s top 5 comment pieces of 2014Benedict Lam takes a look back on the most popular and talked about comment pieces of 2014…
Physiology underpins notion that colds are caught more readily in cool weather The antiviral immune response is diminished at lower temperatures, according to a mouse study published in Proceedings of the National Academy of Sciences.…
Developing studies to test drug safety as a research fellow In her role as principal research fellow at the Drug Safety Research Unit, Deborah Layton uses principles of pharmacoepidemiology to develop studies to help assess the safety of drugs.…