Osteoporosis

Cracking your knuckles will do you no harm

Scientists have used an MRI scanner to observe what happens when you crack your knuckles — a process that does not seem to cause ill health effects.…

Osteoporosis drug shows promise as COPD treatment

Repurposing the bisphosphonate bone drug alendronate relieves symptoms of emphysema associated with chronic obstructive pulmonary disease by targeting alveolar macrophages, according to a study in mice…

Low and high levels of vitamin D associated with cardiovascular deaths, study suggests

The association between cardiovascular disease mortality and vitamin D levels has been investigated in an observational study.…

Zoledronic acid ‘patient card’ would reduce risk of bone tissue death

Use of a patient reminder card has been recommended by a committee of the European Medicines Agency to minimise the risk of jaw osteonecrosis associated with zoledronic acid.…

Osteoporosis: a disease of the modern world?

A lack of vigorous exercise has caused human bones to become weaker over thousands of years.…

Lipophilic bisphosphonates used to target lung cancer

A new generation of lipophilic bisphosphonates has been designed to target cancer, with a zoledronic acid analogue demonstrating efficacy against lung adenocarcinoma.…

Latest trials do not support link between bisphosphonate use and reduced breast cancer risk

Randomised controlled trials fail to confirm association between osteoporosis treatments and decreased breast cancer risk in postmenopausal women.…

Building bones with nutraceuticals

David Appleton and Brian Lockwood discuss bone, osteoporosis and nutraceuticals that can help treat and slow the process of bone depletion.…