Parkinson's disease

Eltoprazine could tackle dyskinesia side effect in Parkinson’s disease, study suggests

Researchers have evaluated the use of eltoprazine, a selective partial agonist at the 5-HT1A and 5-HT1B receptors, for its ability to counteract dyskinesias.…

Perception of drug cost influences placebo response in Parkinson’s disease

Treatment perceived to be expensive, even though it was a placebo, led to a two-fold improvement in motor function in Parkinson’s disease patients compared with a treatment perceived to be cheap.…

Safinamide recommended for approval as Parkinson’s disease therapy

A new medicine that allows Parkinson’s disease patients to spend more of the day symptom-free has been recommended for approval in Europe.…

Gut microbiome altered in Parkinson’s disease

Intestinal microbiome is altered in Parkinson’s disease and is related to the severity of postural instability and gait difficulty, say researchers.…

James Parkinson and the shaking palsy

James Parkinson, who discovered the shaking palsy that established Parkinson’s as a recognised medical condition, died 190 years ago on 21 December 1824…

Merton Sandler (1926-2014)

Merton Sandler was fascinated by investigative medicine and was a passionate researcher, who would often use himself as a test subject.…

Pfizer offers settlement in class action over Parkinson’s drug Cabaser

Company has offered to settle a class action brought by more than 150 patients in Australia who allege they were never warned about the side effects of treatment.…

Parkinson’s disease: treatment

By David Burn, FRCP, MD The treatment of Parkinson’s disease (PD) was revolutionised by the introduction of levodopa in 1967. In the relatively short period of time that has followed, the limitations of levodopa have been recognised and an increasing number of alternative drugs have been develope…

Parkinson’s disease: an overview

PD is the second most common neurodegenerative disease experienced by man, Alzheimer’s disease being the most common. It affects 1 per cent of the population over 65 years of age, rising to 2 per cent over 80 years. It is estimated that 5 per cent of patients are diagnosed before their 40th ye…