Pharmacokinetics

Three decades of Viagra

Sildenafil (Viagra) — the first oral drug for erectile dysfunction to hit the market in 1998 — has been prescribed for more than 64 million men worldwide, and may soon be reclassified as a pharmacy medicine in the UK.…

Basic introduction to knowledge and skills required in new drug development

Introduction to drug disposition and pharmacokinetics, by Stephen H Curry and Robin Whelpton…

New oral anticoagulants for stroke prevention in atrial fibrillation

Around 12,500 strokes are caused by atrial fibrillation (AF) in the UK each year, and 7,100 of these are preventable with appropriate anticoagulation. Four new oral anticoagulants (NOACs) are now available in the UK in addition to warfarin.…

Principles of initiating antimicrobial therapy and empiric prescribing

Healthcare professionals should be aware of the principles of antimicrobial treatment and the need to reduce inappropriate prescribing to retain the effectiveness of drugs currently available.…

Bariatric surgery and the effects on drug pharmacokinetics

Understanding the types of bariatric surgery, their impact on drug pharmacokinetics and specific recommendations for drug regimens following surgery.…

A solid overview of psychotropic drugs

‘Fundamentals of clinical psychopharmacology 4th edition’, edited by Ian M. Anderson and R. Hamish McAllister-Williams.…

Learning about each stage of drug development

‘Basic principles of drug discovery and development’ by Benjamin E Blass.…

Triptan interactions

A number of clinically relevant pharmacokinetic and pharmacodynamic interactions involving 5HT1 receptor agonists are known, although these are not frequently encountered in migraine treatment. …

Breaking down the complex subject of pharmacokinetics

‘Essential pharmacokinetics: a primer for pharmaceutical scientists’, by Thorsteinn Loftsson.…

3D printing: the future of manufacturing medicine?

As the pharmaceutical industry shifts from mass manufacture towards personalised medicine, 3D printing could become part of the drug production line.…