SSRIs and SNRIs for paediatric psychiatric disorders yield only small benefit over placebo The placebo effect played a significant role in the efficacy of antidepressants, which are known to be associated with an increased risk of severe adverse events.…
HRT not linked to early death, study concludes Hormone replacement therapy is not associated with all-cause, cancer or cardiovascular death, according to the results of an 18-year follow-up study.…
Study lends support to genuine efficacy of antidepressants Findings show that the antidepressants citalopram and paroxetine have significant beneficial effects, clearly outperforming placebo.…
Limited evidence for use of gabapentinoids to treat chronic low back pain Analysis of randomised controlled trials assessing the use of gabapentinoids for chronic low back pain confirms that evidence on their use is limited and the drug should be used with caution. …
Screening for HIV in primary care is cost effective and should be promoted, say researchers General practice-based HIV screening is an important public health intervention which should be used more widely, according to a study led by researchers at Queen Mary University of London and the London School of Hygiene and Tropical Medicine…
FDA approves drug to reduce risk of HER2-positive breast cancer returning The US Food and Drug Administration (FDA) has approved neratinib (Nerlynx; Puma Biotechnology) as the first extended adjuvant therapy for early-stage, HER2-positive breast cancer.…
An aspirin before bed reduces risk of pre-eclampsia in pregnant women Low-dose aspirin taken each night before bed significantly reduces the risk of pre-eclampsia in pregnant women, according to research carried out at King’s College London and the University of Exeter.…
Cannabis drug cuts seizures in childhood epilepsy Cannabidiol shows promise in reducing the frequency of convulsive seizures in patients with Dravet syndrome, a rare and severe form of epilepsy.…
Chondroitin sulfate alleviates symptoms in knee osteoarthritis Study shows positive effects of medicine in managing pain and improving mobility in patients with osteoarthritis.…
Bevacizumab as effective as aflibercept for central retinal vein occlusion Bevacizumab is frequently used off-label for treating macular oedema resulting from central retinal vein occlusion (CRVO), despite a lack of supporting data.…
