Personalising antidepressants: should we be genetic testing?

Some health systems are already using pharmacogenomic testing to help tailor treatment for depression, but experts say the evidence for this approach is not quite there yet.
Illustration of a sad man standing with pills in the background

When deciding to prescribe a medicine to alleviate depression, doctors and patients face a fraught process of trial and error. After the initial clinical evaluation, a doctor’s first choice antidepressant has a 50–50 chance of working, and this usually takes several weeks to find out​[1]​.

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