All DOACs recommended for prevention of AF-related stroke, new NICE guideline states

The National Institute for Health and Care Excellence has overturned draft guidance that once-per-day direct oral anticoagulants should only be offered if twice-daily options are not tolerated.

Four direct oral anticoagulants (DOACs) are all recommended as options for people with atrial fibrillation (AF) and a CHA2DS2‑VASc score of 2 or above for the prevention of stroke, new guidance from the National Institute for Health and Care Excellence (NICE) has said.

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