Physical health needs to be promoted in patients with severe mental illness

Schizophrenia is associated with high cardiovascular mortality, research finds

Schizophrenia is associated with high cardiovascular morbidity and mortality. The reasons for this are complex, involving schizophrenia-related factors, poverty, an unhealthy lifestyle, suboptimal medical monitoring and care, and adverse effects of treatment.

Further insights are provided by an analysis of 394 patients with first-episode schizophrenia spectrum disorders. Despite their young age (mean 24 years) and short duration of antipsychotic treatment (mean 47 days), these patients had a high prevalence of dyslipidaemia (56.5%), smoking (50.8%), being overweight or obese (48.3%), prehypertension (39.9%), metabolic syndrome (13.2%) and hypertension (10.0%).

“Clinicians need to pay much more attention to promoting physical health in people with severe mental illness,” write lead author Christoph Correll, from The Zucker Hillside Hospital, New York, and colleagues in JAMA Psychiatry
(online, 8 October 2014). 



[1] Correll CU, Robinson DG, Schooler NR et al. Cardiometabolic Risk in Patients With First-Episode Schizophrenia Spectrum Disorders: Baseline Results From the RAISE-ETP Study. JAMA Psychiatry 2014. doi:10.1001/jamapsychiatry.2014.1314 (accessed 8 October 2014).


Last updated
The Pharmaceutical Journal, PJ, 18 October 2014, Vol 293, No 7832;293(7832):DOI:10.1211/PJ.2014.20066756

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