Anti-obesity agents

Triple agonist drug retatrutide shows 21% weight loss in patients with diabetes

Nearly one-quarter of participants with a baseline BMI of 35 or higher and type 2 diabetes, who took retatrutide 12 mg, lost an average of 61 lbs.…

Counterfeit GLP-1 market ‘inevitable’ without full NHS service, MP says

Labour MP Zubir Ahmed also said a new regulatory body, working between the General Pharmaceutical Council and the Medicines and Healthcare products Regulatory Agency, could help solve issues around the illicit supply of medications.…

Children taking GLP-1s can be at risk of nutritional deficiencies, study finds

Researchers found that vitamin D deficiency was most frequently observed, and the most common deficiency-related complication was nutritional anaemia.…

GLP-1s: what is behind the variation in efficacy?

Researchers are trying to untangle the roles of genetics, access and treatment persistence in the efficacy of GLP-1s. As evidence suggests, weight-loss outcomes are different between patient groups.…

Women with type 2 diabetes more likely than men to develop mental health conditions, study suggests

Researchers also found that both women and men who had a combination of type 2 diabetes mellitus and a mental health condition experienced premature mortality compared with other trajectories.…

UK study to look at semaglutide for alcohol addiction and obesity

The four-year trial will aim to help “guide future care” for alcohol-related liver disease and obesity in the UK.…

MHRA approves orforglipron weight-loss pill

The Medicines and Healthcare products Regulatory Agency said its approval of orforglipron makes the UK the first country in Europe to authorise the medication.…

UK patients being recruited for ribupatide trials

Researchers will assess the efficacy of up to 10mg doses of weight-loss drug ribupatide in patients with or without diabetes over around an 18-month period.…

Incretin-based weight-loss drugs should not be deliberately continued in pregnancy, consensus guidelines state

The guidelines have been drawn up by a multidisciplinary group of experts following a systematic scoping review.…

Around one in five adults would share weight-loss jabs with friends, survey finds

A Pharmacy2U-commissioned survey also found that more than one-quarter of UK adults said that they would share oral weight-loss medication with friends or family.…