Prescribing dilemma: balancing risk and benefit when prescribing anticoagulation in an older patient with falls risk This real-world dilemma examines the decision-making process when considering anticoagulation in older patients.…
Coroner highlights lack of head injury warnings for anticoagulant A patient prescribed apixaban, who died following a fall, was unaware of the risks that the anticoagulant presented in the event of head trauma.…
Case-based learning: women’s health and anticoagulation How considerations for anticoagulation in the presence of heavy menstrual bleeding can change over a woman’s life course.…
Standard-dose DOACs not necessarily better than reduced dose, study results suggest Researchers found that “non-inferiority” of a reduced dose of direct oral anticoagulants could not be determined when compared with a standard dose, with “reliably low rates” of recurrent venous thromboembolism.…
New class of anticoagulant found to ‘overwhelmingly’ reduce bleeding events in patients with atrial fibrillation Experts say the results of this “exciting” two-year study of abelacimab “add to the growing evidence that inhibition of factor XI may preferentially impact thrombosis over haemostasis”.…
Pharmacists made 150,000 patient interventions during anticoagulant safety audits, report finds The results of the two national audits revealed a significant increase in patients with a yellow anticoagulant alert card, from 66.5% in 2021/2023 to 73.3% in 2023/2024.…
Diltiazem use with anticoagulants associated with higher risk of bleeding compared with metoprolol in older people, study finds The study included data from 204,155 Medicare beneficiaries in the United States who filled a prescription for apixaban or rivaroxaban between January 2012 and November 2020.…
NHS England recommends generic apixaban over edoxaban for treatment of atrial fibrillation For patients already taking a direct-acting oral anticoagulant for atrial fibrillation, NHS England advised commissioners to “consider developing local policy to review patients’ current treatment”.…
Coroner advises NHS England to warn prescribers about interaction of tramadol and warfarin The coroner’s report says NHS England’s response “must contain details of action taken or proposed to be taken, setting out the timetable for action” or must explain why no action is proposed.…
Drug for inherited blood clotting does not cut risk of miscarriage, study reveals The rate of live births for women with inherited thrombophilia and recurrent miscarriage was almost the same, whether they were assigned to receive heparin and standard care or standard care only.…