More than 2,000 patients tested in UK’s first routine genotyping project for clopidogrel prescribing Exclusive: The genotyping project at NHS Tayside identified 2,300 patients, 29% of whom emerged as ‘poor’ or ‘intermediate’ CYP2C19-clopidogrel metabolisers.…
Lessons from testing 2,300 patients at the UK’s first CYP2C19 genotyping system Specialist clinical pharmacist Alex Matos explains what his team has learned in the two years since setting up the NHS Tayside project to genotype acute stroke patients with an indication for clopidogrel.…
First gene-editing therapy recommended by NICE to treat people with beta thalassaemia NHS England said that around 460 patients aged 12 years and over could benefit from the treatment.…
PJ view: Current testing for genetic variants risks undoing years of progress on health inequalities It is crucial that the NHS prioritises health equity as pharmacogenomic testing gains traction in day-to-day UK healthcare.…
Screening for gene variants should be broadened to reduce health inequalities, systematic review concludes Study authors have called for an extension to DPYD genetic testing in the UK, to include variants identified in people with African ancestry.…
How AI is transforming drug discovery Pharmaceutical companies and start-ups are harnessing AI to improve speed and reduce costs at every stage of the drug discovery and development process.…
DOACs to be analysed as part of genetic biobank scheme Patients who report adverse effects from direct oral anticoagulants to the Yellow Card scheme may be contacted to provide a blood sample, from which data will then be added to a biobank for researchers to analyse.…
Test yourself: the 2023 CPD and Learning quiz Assess your knowledge on topics ranging from infectious diseases, to professional skills, to cardiology, in our end-of-year CPD and learning quiz.…
UK regulator to consider EMA recommendation to avoid topiramate in pregnancy Exclusive: The UK medicines regulator said it would carefully consider recommendations made by the European Medicines Agency, which were published following a review of data showing an increased risk of developmental disorders among children exposed to topiramate before birth.…
Pharmacists asked for views on implementing pharmacogenetics in the NHS Participants in a survey will be presented with a series of hypothetical options related to using pharmacogenetics in the prescribing process, as part of a pilot programme.…
