MHRA sets out plans to speed up access to rare disease therapies The Medicines and Healthcare products Regulatory Agency said “the rulebook for rare disease therapies will be overhauled" to make it quicker and easier to get therapies tested and approved.…
Bruton tyrosine kinase inhibitors and B-cell malignancies: a guide for pharmacists This learning article with interactive elements provides an overview of the available Bruton tyrosine kinase inhibitors for the treatment of B-cell malignancies to support pharmacists with their use in practice.… Supported content
Genetic testing could prevent three-quarters of avoidable side effects of some medicines, study suggests Researchers found that patients experiencing adverse drug reactions to treatments for psychiatric disorders and cardiovascular problems could benefit the most from personalised prescribing with pharmacogenomics.…
NICE recommends once-weekly injection for severe blood clotting disorder Efanesoctocog alfa, a once-weekly treatment for patients with severe haemophilia A, removes the need for frequent dosing, owing to its effective bleeding control.…
More than 2,000 patients tested in UK’s first routine genotyping project for clopidogrel prescribing Exclusive: The genotyping project at NHS Tayside identified 2,300 patients, 29% of whom emerged as ‘poor’ or ‘intermediate’ CYP2C19-clopidogrel metabolisers.…
Lessons from testing 2,300 patients at the UK’s first CYP2C19 genotyping system Specialist clinical pharmacist Alex Matos explains what his team has learned in the two years since setting up the NHS Tayside project to genotype acute stroke patients with an indication for clopidogrel.…
First gene-editing therapy recommended by NICE to treat people with beta thalassaemia NHS England said that around 460 patients aged 12 years and over could benefit from the treatment.…
PJ view: Current testing for genetic variants risks undoing years of progress on health inequalities It is crucial that the NHS prioritises health equity as pharmacogenomic testing gains traction in day-to-day UK healthcare.…
Screening for gene variants should be broadened to reduce health inequalities, systematic review concludes Study authors have called for an extension to DPYD genetic testing in the UK, to include variants identified in people with African ancestry.…
How AI is transforming drug discovery Pharmaceutical companies and start-ups are harnessing AI to improve speed and reduce costs at every stage of the drug discovery and development process.…
