Breast cancer

Goserelin protects against ovarian failure in women treated for breast cancer

Research suggests that the gonadotropin-releasing hormone agonist goserelin can help protect against ovarian failure in women treated for breast cancer.…

Short-term use of hormone replacement therapy linked to ovarian cancer

Women who take hormone replacement therapy (HRT) are at a higher risk of developing ovarian cancer, even if it is taken for less than five years, suggest the results of a meta-analysis published in The Lancet.…

Breast cancer drug palbociclib gets expedited approval in United States

The US Food and Drug Administration has approved palbociclib (Ibrance; Pfizer) for advanced (metastatic) breast cancer under its accelerated approval programme.…

Paclitaxel plus trastuzumab tested in node-negative HER2-positive breast cancer

Researchers report promising results for paclitaxel plus trastuzumab in some patients with node-negative HER2-positive breast cancer.…

NHS England drops therapies from cancer drugs fund to save £80m

A total of 25 clinical indications will be removed from the government’s cancer drugs fund list, NHS England has announced.…

Chemoprevention with tamoxifen cuts risk of breast cancer by almost 30%

Tamoxifen used in primary prevention cuts the risk of breast cancer by around 30% and this benefit lasts for at least 20 years, a long-term follow-up of the International Breast Cancer Intervention Study shows.…

Sequencing cancer genomes to tailor treatments to individual patients

Screening for hundreds of mutations in tumours is the most promising route to customised drug treatments for cancer.…

Forces driving the evolution of biologics into biosimilars and biobetters

As demand for biologics increases, manufacturers are devising strategies to maximise their returns on investment and benefit patients.…

Criticism voiced over new rules for Cancer Drugs Fund

Cancer charities and the pharmaceutical industry have expressed concerns over the way cancer medicines are appraised after a revised process for assessing drugs available through the Cancer Drugs Fund was published by NHS England.…

Eribulin improves survival in women with advanced breast cancer

Eribulin improves overall survival in women with advanced breast cancer, with the greatest benefit seen in women with triple-negative disease, new research suggests.…