Central nervous system agents

Pharmacists encouraged to report GLP-1 side effects amid pharmacogenomics study

The Medicines and Healthcare products Regulatory Agency has called on healthcare professionals to submit Yellow Card reports on behalf of patients who develop acute pancreatitis while using GLP-1 receptor agonists.…

Pharmacy bodies warn that demand for weight-loss drug will outstrip supply

Around 220,000 patients could be prescribed Mounjaro in the first three years of the drug's availability to NHS patients in England, the National Institute for Health and Care Excellence has estimated.…

Case-based learning: understanding and managing levetiracetam-induced psychiatric symptoms

This article highlights the psychiatric adverse effects of levetiracetam, emphasising the importance of recognising these effects rather than attributing them to an organic diagnosis.…

Bipolar disorder in adults: symptoms, diagnosis and management

A detailed overview of the different types of bipolar disease and treatments.…

UK government says it does not support safe drug consumption rooms

Speaking at a House of Commons Scottish Affairs Committee inquiry into the Glasgow safe drug consumption facility, the minister for policing and crime prevention said the Westminster government would “not be amending the Misuse of Drugs Act”.…

Eye disorder is a ‘very rare’ side effect of weight-loss drugs, concludes EMA review

The review found that non-arteritic anterior ischemic optic neuropathy may affect up to 1 in 10,000 people taking semaglutide medicines.…

Study finds association between GLP-1 use and macular degeneration in diabetes

Researchers found that patients with longer durations of exposure to glucagon-like peptide-1 receptor agonists were associated with a higher risk of developing neovascular age-related macular degeneration.…

MHRA urges women taking weight-loss drugs to use effective contraception

Guidance published by the medicines regulator has warned that patients trying to conceive should remain on contraception for a “wash-out” period after stopping GLP-1 receptor agonists.…

NHS England looks to tender contract for behavioural support for patients prescribed tirzepatide in primary care

The NHS England document said that patients prescribed tirzepatide in primary care settings will receive “high-quality behavioural wrap-around care” as well as clinical support.…

Antidepressants ‘substantially increase risk’ of low blood pressure when standing up in older people, study results suggest

Researchers found that patients aged over 60 years who were prescribed selective serotonin re-uptake inhibitors were at a four-fold increased risk of postural hypotension in first four weeks of use.…