NSAIDS - Non-Steroidal anti-inflammatory agents

NSAID prescribing in high-risk groups is a major source of avoidable harm, study finds

The study estimated that the practice could have caused more than 6,000 lost years of good health across England over a ten-year period.…

NSAIDs used alongside hormonal contraception increase risk of blood clots, research suggests

Researchers concluded that the absolute risk of a venous thromboembolic event remains low in concomitant use of hormonal contraception and non-steroidal anti-inflammatory drugs.…

‘Exciting’ trial results show NSAID taken with emergency contraception could improve efficacy

Using data from 860 people in Hong Kong, researchers found that the percentage of pregnancies prevented was significantly higher in those who took piroxicam plus levonorgestrel compared with those assigned to take placebo and levonorgestrel.…

Avoid prescribing NSAIDs after 20 weeks of pregnancy, advises medicines regulator

The regulator has advised clinicians that non-steroidal anti-inflammatories after 20 weeks of pregnancy should only be prescribed if clinically required and at the lowest dose for the shortest amount of time.…

NSAIDs fail to reduce joint inflammation for people with arthritis of the knee, study results show

Comparing two groups of people with synovitis, researchers found that those treated with long-term oral non-steroidal anti-inflammatory drugs had worse synovitis than those not treated with the drugs.…

Antibiotics cut the risk of stomach bleeding caused by using aspirin in the long term, study results show

The researchers said the benefits of antibiotic treatment were strongest in the time period immediately after treatment.…

Non-steroidal anti-inflammatory drugs linked with heart failure in patients with diabetes

Researchers found that NSAID use in any period was linked with a 43% increased risk of subsequent hospitalisation for heart failure.…

Routine NSAID use not associated with poorer outcomes in patients hospitalised with COVID-19

Routine use of non-steroidal anti-inflammatory drugs might confer “modest” survival benefit for patients hospitalised with COVID-19 and is not associated with poorer outcomes, the results of a study published in the Journal of Clinical Medicine have suggested.…

Presenting the GI evidence of ibuprofen

Concerns about OTC ibuprofen could come from some of the guidance seen for prescription doses of the drug, but is this caution supported by the evidence?…

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Paracetamol or ibuprofen can be used to treat the symptoms of COVID-19, says NHS England

The NHS has changed its advice on only taking paracetamol to treat the symptoms of COVID-19 and now says that patients can take either paracetamol or ibuprofen to self-medicate for symptoms such as fever or headache.…