Illustration of many hands reaching for a medication, most white, with a darker skinned hand trying to read dosage and side effects information but it is pixelated/obscured

Closing the ethnicity gap in pharmacogenomics

An overwhelming reliance on data from people with white, European ancestry threatens to make pharmacogenomics a poor tool for patients from other backgrounds.

Anil Kapoor came from a family of doctors. Having become a leading urologist and renal transplant surgeon at St Joseph’s, Hamilton, Canada, it came as a shock when — aged only 58 years — he received a diagnosis of colorectal cancer. He was prescribed a chemotherapy regimen called ‘FOLFOX’, which includes 5-fluorouracil (5-FU), a medicine used to treat several different cancers. “None of us knew anything about these drugs,” says Vimal Kapoor, an emergency doctor at Markham Stouffville Hospital in Markham, Canada, and Anil’s younger brother.

Register for free to keep on reading

Access two premium articles as a registered user.

Register

Already an RPS member or registered? Log in

Register for free to keep on reading

Access two premium articles as a registered user.

Register

Already an RPS member or registered? Log in

Register for free to keep on reading

Access two premium articles as a registered user.

Register

Already an RPS member or registered? Log in

Register for free to keep on reading

Access two premium articles as a registered user.

Register

Already an RPS member or registered? Log in

Last updated