Migraine: pathophysiology, recognition and management

By the end of this article, you should be able to:

• Understand the prevalence of migraine in the UK, its burden on individuals and economic impact;
• Understand the pathophysiology and stages of migraine and how it is diagnosed;
• Describe the main components of migraine treatment (lifestyle management, acute treatments, prophylactic agents), and the pharmacological and non-pharmacological options available to prescribers; 
• Describe the mechanism of action for CGRP monoclonal antibodies and CGRP receptor antagonists (gepants).