Digestive system signs and symptoms

Linaclotide, lubiprostone and prucalopride interactions

How to avoid potential pharmacokinetic and pharmacodynamic interactions with the latest medicines for managing constipation.…

Constipation: managing the condition in adults

How to assess patients with constipation and select the right treatment to minimise the risk of complications.…

Public health campaign highlights heartburn link to cancer

People who have daily heartburn for three consecutive weeks may be at risk from oesophageal or stomach cancer and are advised to visit their GP, according to a new public health campaign.…

OTC domperidone will be missed

The antiemetic domperidone’s reclassification shows the importance of pharmacovigilance, but the loss of such a useful over-the-counter medicine ought to have been better communicated to community pharmacies.…

Naloxegol effective in treating opioid-induced constipation

Naloxegol has shown efficacy in two phase III clinical trials.…

Microbiomics: its growing significance in the world of medicines testing

Gut bacteria are now known to do more than just digest food. Kalliopi Dodou and Paul Whiteley take a look at microbiomics in our latest science article.…

Zinc supplements may reduce pneumonia and diarrhoea

Zinc supplementation may reduce the incidence of pneumonia by 41 per cent and that of diarrhoea by up to 25 per cent, say the Zinc Investigators’ Collaborative Group. Writing in the Journal of Pediatrics (1999;135:689), they report a pooled analysis of 10 trials (published and unpublished) in …