New small molecule drug shows promise in refractory rheumatoid arthritis Rheumatoid arthritis patients who do not respond to treatment with biologic therapies may find relief in baricitinib, a new small molecule drug, according to the results of a phase III study published in The New England Journal of Medicine.…
Paracetamol ineffective in treating osteoarthritis, meta-analysis finds Paracetamol is not clinically effective for alleviating pain and improving physical function in patients with osteoarthritis, the largest analysis of randomised trials of analgesics for osteoarthritis published to date has found. …
Vitamin D supplements in pregnancy make no difference to bone strength of babies Vitamin D supplements taken by pregnant women have no significant effect on the bone strength of their babies, according to the results of a study published in The Lancet Diabetes and Endocrinology.…
Bisphosphonate prevents bone loss during HIV treatment A dose of zoledronic acid at the same time as antiretroviral therapy reduces bone resorption, a phase II clinical trial suggests. …
The man who discovered ibuprofen Ibuprofen is one of the world’s best selling anti-inflammatory painkillers. Its pioneer, Stewart Adams, now 92 years old, tells Julia Robinson about how and why his discovery came to fruition.…
Chronic Kidney Disease – Mineral and Bone Disorder: pathophysiology and treatment How the pathophysiological mechanisms behind development of Chronic Kidney Disease - Mineral and Bone Disorder can be managed, using appropriate therapeutic interventions to prevent complications.…
How to win national recognition through rheumatology ‘I Love My Pharmacist’ winner Emily Rose has saved the NHS £200,000 as a result of her new patient monitoring pathway. Here she tells Julia Robinson how she accidently fell into rheumatology, and why she intends on rolling the service out to other departments.…
Gene editing used to treat muscular dystrophy in mice CRISPR/Cas9 system injected into muscle or bloodstream restored function of dystrophin gene, marking an important step in gene therapy research.…
Higher doses of vitamin D heighten risk of falls in older people Older people at risk of falls are worse off taking high doses of vitamin D, suggest the results of a study published in JAMA Internal Medicine on 4 January 2016, leading experts to recommend against high-dose supplementation.…
FDA approves URAT1 inhibitor lesinurad to treat gout A new treatment for gout that blocks the reabsorption of uric acid in the kidneys has been approved by the US Food and Drug Administration.…
