Medication restrictions for patients receiving CAR-T therapy

Prior reading

Before reading this article, you should have read ‘Implementing chimeric antigen receptor T-cell therapy in practice‘.

Learning objectives

After reading this article, you should be able to:

• Describe the stages of the CAR-T therapy pathway from collection of starting material to administration of the final product;
• Understand how CAR-T therapy is manufactured;
• Know the relevant medication restrictions and at which stages of the cycle that drug wash out periods are important;
• Understand which drug factors may influence quality of CAR-T starting material or product.