Animal experimentation

Experimental diabetes drug shows promise in Parkinson’s disease

An experimental drug originally developed for type 2 diabetes has shown early promise as a treatment for Parkinson’s disease, say researchers who are now planning a clinical trial in humans. …

Small molecule vaccine protects against UTI in mice

A vaccine using siderophores reduced bacterial burden in the urine and kidneys of mice, researchers report.…

Researchers create star-shaped device that can deliver drug dose over two weeks

US researchers have developed a star-shaped long-lasting drug device that resides in the stomach and can deliver a controlled drug dose over a period of up to two weeks.…

Laquinimod inhibits secondary progressive MS in mouse model

Laquinimod reduced the number of mice who developed multiple sclerosis in one model, and slowed disease progression in another.…

Excess dietary zinc increases susceptibility to C difficile

Researchers found that mice given a high-zinc diet were more likely to experience Clostridium difficile infection at lower antibiotic doses.…

Newly identified compound could both treat and prevent malaria

Bicyclic azetidines have the potential to both cure malaria and prevent malaria transmission, study shows.…

Antibiotic gel crosses eardrum to treat middle ear infections

A one-dose application of an antibiotic gel into the ear could make it easier to treat middle ear infections in children, say US researchers.…

Progesterone accelerates recovery from flu virus

Progesterone was found to enhance recovery from influenza in mice and so could also have benefits for humans during disease outbreaks, say researchers…

Medication-releasing contact lens could treat glaucoma

Contact lenses that release latanoprost are at least as effective as latanoprost drops in reducing intraocular pressure, study finds.…

Alzheimer’s inflammation targeted with period pain NSAID

Flufenamic acid and mefenamic acid successfully reduced inflammation and memory deficits in rodent model of Alzheimer’s disease.…