EMA outlines steps towards ethical use of medicines in animal testing The European Medicines Agency has published its first report on how it is encouraging drug companies to use alternatives to animal testing in all stages of product development and manufacture.…
Atypical antipsychotic causes weight gain by targeting serotonin receptor 2C Study suggests that serotonin 2C receptor agonists may be useful in preventing metabolic side effects associated with taking atypical antipsychotics.…
Research identifies potential target for treating inflammatory skin diseases Targeting Ripk1 could be an effective treatment for skin conditions such as eczema and psoriasis, a study finds.…
Study into colon cancer highlights usefulness of pig model The pig model can help in developing preventive strategies against gut bacterial dysbiosis and inflammation-promoted diseases, such as colon cancer, researchers find.…
Researchers find way to overcome Zika vaccine–Dengue virus conundrum Researchers have developed a vaccine that provides protection against the Zika virus in mice without increasing susceptibility to Dengue virus infection.…
Beta-blockers reverse heart failure gene expression A study in Scientific Reports reveals beta-blockers as potential modulators of cardiac gene expression.…
Researchers dispute the therapeutic mode of action of a ketamine metabolite A study in Nature contradicts a previous report on synaptic NMDAR inhibition by a ketamine metabolite, a potential antidepressant.…
Prenatal paracetamol exposure alters brain and reproductive tract development in male mice The need to limit the widespread exposure and use of paracetamol by pregnant women has been emphasised in a recent study published in the journal Reproduction.…
Effects of ADHD drug on the brain are reversible, study suggests Even high doses over an extended treatment period were not detectable in brain regions after a month’s abstinence, according to animal study.…
Flu might increase risk of Parkinson’s disease Researchers observe a link between flu virus infection and Parkinson’s disease pathology, strengthening the case for flu vaccination and prompt antiviral treatment.…