Animal experimentation

Injected antibodies provide long-term protection against HIV

 Trial results show extended protection against HIV in monkeys treated with monoclonal antibodies.…

COX-2 inhibitors might prevent pre-eclampsia

Cyclooxygenase (COX)-2 inhibitor celecoxib reversed early signs of pre-eclampsia in pregnant mice.…

Modified bleomycin reduces toxic side effects

Mouse study shows deglyco-bleomycin could be less toxic alternative to standard bleomycin.…

‘Neurostatin’ prevents Alzheimer’s-related amyloid formation

Roundworm study shows bexarotene could inhibit early step of amyloid-beta aggregation.…

Peptide antiviral “a real step forward” in search for flu treatment

Ongoing mutations of influenza virus surface proteins mean a different flu vaccine must be used each year, but researchers think they may have found a novel antiviral drug that could protect against a variety of influenza strains.…

Painkiller use during pregnancy linked to reduced fertility in offspring

Indomethacin and paracetamol use in female rats results in offspring having low ovary weights and reduced litter sizes.…

Researchers unravel function of HIV defence protein

Researchers investigate why TRIM5α protein lost ability to degrade HIV in rhesus monkey study.…

Side effects of Parkinson’s treatment reduced by blocking brain protein

Targeting p11 protein in dopamine-responsive region of the brain shows promise in mouse model of Parkinson’s disease.…

Gene editing used to treat muscular dystrophy in mice

CRISPR/Cas9 system injected into muscle or bloodstream restored function of dystrophin gene, marking an important step in gene therapy research.…

Cancer metastasis could be prevented with immune-blocking strategy

Researchers find immune system involved in metastasis-boosting microenvironment in mice.…