Large malaria genome study highlights surprising number of potential drug targets A large-scale study of malaria gene function reveals an abundance of essential parasite genes that could be targets for new antimalarial drugs.…
Serum serotonin levels could identify sudden infant death syndrome cases Study reveals serotonin metabolism abnormalities as contributing factors to sudden infant death syndrome and suggests serotonin serum levels as a forensic biomarker.…
Analysis estimates more than 30 Alzheimer’s drugs will have launched by 2022 Over the next 5 years, 27 phase III and 8 phase II Alzheimer’s drugs may be launched, according to a pipeline analysis carried out by ResearchersAgainstAlzheimer’s…
Beta-blockers reverse heart failure gene expression A study in Scientific Reports reveals beta-blockers as potential modulators of cardiac gene expression.…
Researchers dispute the therapeutic mode of action of a ketamine metabolite A study in Nature contradicts a previous report on synaptic NMDAR inhibition by a ketamine metabolite, a potential antidepressant.…
Prenatal paracetamol exposure alters brain and reproductive tract development in male mice The need to limit the widespread exposure and use of paracetamol by pregnant women has been emphasised in a recent study published in the journal Reproduction.…
Psoriasis drug approved by FDA The US Food and Drug Administration (FDA) has approved Tremfya (guselkumab) for the treatment of adults with moderate to severe plaque psoriasis…
Effects of ADHD drug on the brain are reversible, study suggests Even high doses over an extended treatment period were not detectable in brain regions after a month’s abstinence, according to animal study.…
Multiple myeloma: an expensive revolution New treatments for this rare form of cancer have transformed patient survival rates, but the benefits have come with huge costs.…
‘Liquid biopsy’ guides PARP inhibitor treatment of prostate cancer Analysis of circulating free tumour DNA in blood shows how well cancer therapy is working and can inform further treatment.…