Heart failure

Diuretic withdrawal appears safe in patients with stable chronic heart failure, trial shows

Patients who have chronic but stable heart failure should have their diuretic use reconsidered, researchers have suggested.…

Androgen deprivation therapy ‘increases heart failure risk’

Patients with prostate cancer treated with androgen deprivation therapy were 72% more likely to experience heart failure than those unexposed to the therapy, a study has shown.…

Pathophysiology and management of heart failure

Ensuring patients are optimised on maximum tolerated doses of medicines in heart failure with reduced ejection fraction is essential in minimising the burden of the condition.…

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Painkiller linked to increased risk of heart problems

More clear warnings should be given about the risks of diclofenac, say researchers who found a higher risk of heart attack and stroke associated with its use.…

Aspirin lowers risk of death in people with concomitant heart failure and diabetes

Aspirin reduces the risk of all-cause death or hospitalisation for heart failure in patients with concomitant type 2 diabetes and heart failure but increases the risk of non-fatal heart attack or stroke.…

ADT increases some cardiovascular risks in men with localised prostate cancer

A study finds that the use of androgen deprivation therapy to treat prostate cancer is associated with a heightened risk of developing cardiovascular disease and recommends closer cardiac monitoring during treatment…

Pharmacists exporting sacubitril/valsartan should consider indirect impact on patient safety

I wish to highlight an ongoing problem to the readers of The Pharmaceutical Journal with shortages of one of our newer heart failure treatments sacubitril/valsartan. Heart failure (HF) is the most malignant form of heart disease and has outcomes comparable with most common cance…

Off-label use of sildenafil in valvular heart disease should be avoided

A study presented at the European Society of Cardiology Congress reported the effects of sildenafil in patients with valvular heart disease.…

My journey from analytical chemist to heart failure specialist pharmacist

Helping patients to make sense of a serious and complex long-term condition is the most interesting part of my role, says Rocco Hadland.…

Hundreds more people surviving heart failure

Hundreds more patients admitted to hospital with heart failure are surviving because of improvements in care, an independent audit commissioned by the NHS has found.…