Kidney diseases - Renal disorders

How my part-time medicines safety PhD changed prescribing practice for older people

Pharmacist Su Wood’s work on estimating reduced kidney function led to a major change in national recommendations for prescribing in older people.…

At last, a new treatment option for diabetes-related chronic kidney disease

Guideline-changing trial results released earlier in 2019 suggest that SGLT2 inhibitors could be a viable treatment solution for patients with diabetes and evidence of kidney damage.…

SGLT2 inhibitor lowers risk of kidney failure in type 2 diabetes

Patients with type 2 diabetes mellitus and chronic kidney disease have a lower risk of kidney failure and cardiovascular events if they are treated with canagliflozin, research has confirmed.…

Increased intensity plus adherence maximises statin benefits

High adherence to intensive lipid-lowering therapy provides the greatest risk reduction for cardiovascular events, a study in JAMA Network Open has shown.…

Lack of evidence to support statin use in non-cardiovascular conditions

There is a lack of ‘convincing’ evidence that statins improve outcomes in non-cardiovascular conditions, such as diabetes, a review has shown.…

Diagnosis and management of anaemia in adults with chronic kidney disease

An overview of the treatments for anaemia in chronic kidney disease and the tests needed to prescribe and assess their effectiveness.…

Uncertainty over anticoagulation risks and benefits in CKD patients with AF

The risk of both stroke and haemorrhage increases as chronic kidney disease progresses, which can complicate the decision on whether to begin anticoagulation in those with concomitant atrial fibrillation.…

Sick days off – a simple strategy to prevent acute kidney injury and other adverse drug reactions

Adverse drug reactions (ADRs) are common and account for around 5% of all[1] , and up to 16.6% in the elderly[2] hospital admissions. Approximately 10%–20% of inpatients suffer at least one ADR during their hospital stay. ADRs often adversely affect the individual’s qu…

NICE recommends statins should be offered to everyone with chronic kidney disease

Healthcare professionals should offer statins to the millions of people who have chronic kidney disease to help manage their increased risk of cardiovascular disease, NICE has urged…

Identifying the risk of acute kidney injury in primary care

It is thought that up to 60% of acute kidney injury (AKI) cases presented in hospital begin in primary care[1] . In the UK, AKI costs the NHS over £1bn each year[2] . Up to one-fifth of patients admitted to hospital in an emergency have AKI, which, if untreated, can lead to c…