Small molecule could pave way for novel vaccine adjuvants Identification and characterisation of a small molecule that targets protein receptors that stimulate the immune system could lead to novel vaccine adjuvants and anti-tumour agents.…
Low doses of sequential antibiotics could treat infections, study finds Sequential therapy with two synergistic antibiotics over a period of 96 hours cleared bacterial infection in an in vitro treatment model of Escherichia coli.…
Antihistamine could be used as a cheaper hepatitis C therapy, study suggests An anti-allergy treatment is effective in treating hepatitis C virus, a study has found, raising hopes of an affordable weapon in the fight against the virus. …
Tau oligomers targeted with promising Alzheimer’s therapy Scientists report promising early findings with an anti-tau oligomer specific monoclonal antibody that reversed memory deficits in mice with Alzheimer’s disease.…
Researchers develop test that predicts severe immune reaction to biologics A test that uses cells from a single donor’s blood to predict whether a new drug will cause a severe immune reaction in humans has been developed by researchers at Imperial College London.…
Medicine errors can be avoided with clearer IV bag labels, research suggests Redesigning the labels of intravenous medicine bags can “significantly” reduce the risk of administering the wrong drugs during an operating theatre emergency.…
Nucleic acids made into furry nanoballs modulate immune system Short nucleic acids mounted on to nanoparticles could prove to be novel immunomodulators, according to research published in PNAS.…
Energy restriction could tackle drug-resistant epilepsy Shutting down a metabolic pathway that fuels misfiring neurons can suppress seizures in mice, find researchers who predict a fresh approach to developing antiepileptic drugs.…
Osteoporosis drug shows promise as COPD treatment Repurposing the bisphosphonate bone drug alendronate relieves symptoms of emphysema associated with chronic obstructive pulmonary disease by targeting alveolar macrophages, according to a study in mice…
Tuberculosis: New drugs from the sea A team of researchers from a German university has isolated a series of secondary metabolites from the marine sponge Callyspongia aerizusa that have anti-TB activity.…