Study shows how glucocorticoids tightly control the inflammatory response IRAK-M, a key negative regulator of inflammatory pathways, may represent a new therapeutic target to suppress bacteria-induced inflammation, say researchers.…
Oestrogen receptor ligands show promise for treating endometriosis Researchers studying endometriosis have discovered a potential way to treat the disease that avoids many of the side effects seen with existing therapies.…
ATR inhibitors induce cell death in ALT-positive osteosarcoma and glioblastoma cells ATR inhibition may be a useful treatment approach in cancers that use the alternative lengthening of telomeres (ALT) pathway to overcome cell death.…
Physiology underpins notion that colds are caught more readily in cool weather The antiviral immune response is diminished at lower temperatures, according to a mouse study published in Proceedings of the National Academy of Sciences.…
Researchers unearth novel antibiotic without detectable resistance Researchers using an innovative process have discovered a new antibiotic with properties that appear to prevent the development of resistance.…
Malaria eradication: blocking transmission to mosquitoes To wipe out malaria, researchers are racing to develop a vaccine that protects mosquitoes from infection.…
Scientists develop drug that curbs weight gain without reducing food intake Scientists have developed a drug that curbs weight gain and corrects the metabolic defects associated with obesity without reducing food intake.…
Verapamil increases anti-tuberculosis activity of bedaquiline Researchers have shown that giving bedaquiline along with the calcium channel blocker verapamil can result in more potent antibacterial effects.…
Researchers pinpoint new approach to treating obesity Researchers have identified group 2 innate lymphoid cells for the first time in human white adipose tissue and shown that it limits obesity.…
Researchers examine why SSRIs take time to work Researchers have shown that serotonergic neurons release both serotonin and glutamate, thereby transmitting a dual signal with behaviourally distinct effects.…