Virus-mimicking TB may offer therapeutic opportunities A study shows that TB bacteria release a section of DNA, a virus-mimicking molecule called c-di-AMP, and its behaviour offers drug and vaccine possibilities.…
Anti-VEGF therapies could have role in treating TB Bevacizumab, an anti-VEGF drug, was able to normalise granuloma vasculature, improve the delivery of small molecules and decrease hypoxia in a rabbit model of tuberculosis.…
2014: The Pharmaceutical Journal’s news in review Looking back at some of the biggest news stories from the past year. …
Metformin shows promise as anti-tuberculosis drug A promising candidate in the search for alternative treatments for Mycobacterium tuberculosis is the antidiabetic drug metformin.…
Effective treatments lagging behind for multidrug-resistant TB, says WHO There are still major gaps in delivering effective treatments to patients suffering from multidrug-resistant tuberculosis, a report finds.…
Conflict in Ukraine leads to disruption to HIV and TB treatmentPeople in Ukraine infected with HIV/AIDS or tuberculosis have faced interrupted treatment, says a UN report on the protracted conflict.…
Janssen and Novartis pick up 2014 Prix Galien awards Janssen and Novartis scooped prizes at the UK Prix Galien Awards for the first new drug for tuberculosis (TB) in 40 years and the first broadly protective meningitis B vaccine.…
Paediatric formulations of tuberculosis drugs are urgently needed as the disease re-emerges Unless there are new paediatric formulations of drugs for tuberculosis, it is likely that multidrug resistant strains of the disease will develop.…
Bedaquiline in multi-drug resistant tuberculosis The first new anti-tuberculosis drug since 1967 could revolutionise therapy and tackle resistant strains.…
