Best practice for medicines use in neonates An overview of pharmacokinetic and pharmacodynamic considerations when treating neonates, and the impacts on drug absorption, metabolism and elimination.…
Widespread pharmacogenomic testing in psychiatry needs a stronger evidence base More research into the genomic factors influencing psychiatric medicines response is needed before widespread pharmacogenomic testing can be justified.…
NICE recommends drug treatment for long-term insomnia Daridorexant has been recommended as a second-line treatment for long-term insomnia by the National Institute for Health and Care Excellence.…
Children and young people with asthma: pharmacological management and monitoring The second of our two-part series on asthma in children and young people outlines pharmacological management and appropriate monitoring of the condition.…
How to advise women on the safe use of medicines while breastfeeding Pharmacists should understand the pharmacokinetic principles influencing a drug’s passage through breast milk to confidently promote breastfeeding as an important public health measure.…
Should we be genetic testing before prescribing analgesics? Managing pain is difficult because there are various factors that can influence how it is perceived, but pharmacogenomic testing may be able to help fine tune pharmaceutical interventions.…
How critical illness impacts drug pharmacokinetics and pharmacodynamics Critical illness can affect how drugs work in the body and how the body reacts to drugs. This can have important implications for treatment and the risk of adverse effects.…
How codeine metabolism affects its clinical use A deeper understanding of codeine’s unique pharmacokinetic profile is required to ensure the best analgesic outcomes for patients.…
Codeine should not be available over the counter, says chair of opioid expert working group Low-dose codeine should no longer be available to buy over the counter, the chair of the UK’s Commission on Human Medicines opioid expert working group has said.…
Recent advances in the oral delivery of biologics An overview of the key physiological barriers to oral delivery of biologics and the strategies to overcome them that are currently being tested.…
